Tex19.1tm2.1(Tex11)Jw
Targeted Allele Detail
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Symbol: |
Tex19.1tm2.1(Tex11)Jw |
Name: |
testis expressed gene 19.1; targeted mutation 2.1, Jeremy Wang |
MGI ID: |
MGI:5788290 |
Synonyms: |
Tex19KI(W118R) |
Gene: |
Tex19.1 Location: Chr11:121036969-121039140 bp, + strand Genetic Position: Chr11, 85.0 cM
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Alliance: |
Tex19.1tm2.1(Tex11)Jw page
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Allele Type: |
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Targeted (Inserted expressed sequence, Null/knockout) |
Mutations: |
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Insertion, Single point mutation
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Tex19.1tm2.1(Tex11)Jw expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Tex11 (MGI:1933237) |
with mutation W118R |
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Mutation details: The open coding region in exon 3 was replaced with the Tex11 open reading frame with a T to A point mutation that results in the amino acid substitution of arginine for tryptophan at position 118. This mutation corresponds to a mutation in sterile human males. Cre-mediated recombination removed the selection cassette inserted downstream of the inserted expressed sequence.
(J:229429)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tex19.1 Mutation: |
10 strains or lines available
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Original: |
J:229429 Yang F, et al., TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse. EMBO Mol Med. 2015 Sep;7(9):1198-210 |
All: |
1 reference(s) |
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