Chrna9^tm1Bjmy
Targeted Allele Detail

Summary

• Symbol: Chrna9^tm1Bjmy
• Name: cholinergic receptor, nicotinic, alpha polypeptide 9; targeted mutation 1, Barbara J Morley
• MGI ID: MGI:5787807
• Synonyms: Chrna9^tm1Geno
• Gene: Chrna9 Location: Chr5:66092264-66134669 bp, + strand Genetic Position: Chr5, 33.84 cM
• Alliance: Chrna9^tm1Bjmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220194
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed the selection cassette and exons 1 and 2. This allele is derived fromChrna9^tm2Geno (J:220194, J:268887)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chrna9 Mutation: 39 strains or lines available

References

• Original: J:220194 Smith ML, et al., Acetylcholine receptors in the retinas of the alpha7 nicotinic acetylcholine receptor knockout mouse. Mol Vis. 2014;20:1328-56
• All: 10 reference(s)