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Targeted Allele Detail
Symbol: Atp13a2tm1.1Wtd
Name: ATPase type 13A2; targeted mutation 1.1, William T Dauer
MGI ID: MGI:5779523
Synonyms: Apt13a2-flx
Gene: Atp13a2  Location: Chr4:140986873-141007330 bp, + strand  Genetic Position: Chr4, 73.29 cM
Germline Transmission:  Earliest citation of germline transmission: J:221680
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 2 followed by an FRT-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:221680)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp13a2 Mutation:  40 strains or lines available
Original:  J:221680 Kett LR, et al., alpha-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015 Apr 8;35(14):5724-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory