Gt(ROSA)26Sor^{tm1.1(Adgrb1)Ravi}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(Adgrb1)Ravi}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kodi S Ravichandran
• MGI ID: MGI:5776722
• Synonyms: R26^CTV-Bai1, Tg BAI1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(Adgrb1)Ravi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224549
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(Adgrb1)Ravi} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Adgrb1 (MGI:1933736)

• Mutation details: The targeting construct introduced into the locus a wild-type sequence. Cre-mediated recombination removed a floxed STOP cassette upstream of the inserted sequence. (J:224549)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1084 strains or lines available

References

• Original: J:224549 Fond AM, et al., Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1. J Clin Invest. 2015 Jul 1;125(7):2748-58
• All: 3 reference(s)