Tg(PRNP)2019Pcg
Transgene Detail

Summary

• Symbol: Tg(PRNP)2019Pcg
• Name: transgene insertion 2019, Peter Griffiths
• MGI ID: MGI:5775986
• Synonyms: Tg(BoPrP)2019
• Transgene: Tg(PRNP)2019Pcg Location: unknown
• Alliance: Tg(PRNP)2019Pcg page

Transgene origin

• Strain of Origin: FVB/NIco

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(PRNP)2019Pcg expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  cattle	PRNP (281427)

• Mutation details: The transgene comprises a 60-kb DNA fragment containing the bovine prion protein gene (PRNP) (GenBank: AJ298878) derived from clone D18330 of bovine bacterial artificial chromosome (BAC) library 750 from the German Resource Center for Genome Research (RZPD, Resourcenzentrum Primrdatenbank). Mice bearing this transgene express bovine prion protein from its own promoter in brain and other tissues. (J:82809, J:232471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:232471 Veterinary Laboratories Agency, Preparation of more sensitive bioassay models for the improved detection, differentiation and diagnosis of the BSE agent. SID 5 Research Project Final Report, DEFRA Project Code SE1753. 2009
• All: 2 reference(s)