Piwil4^tm1.1Wyan
Targeted Allele Detail

Summary

• Symbol: Piwil4^tm1.1Wyan
• Name: piwi-like RNA-mediated gene silencing 4; targeted mutation 1.1, Wei Yan
• MGI ID: MGI:5775938
• Synonyms: Miwi2^lox
• Gene: Piwil4 Location: Chr9:14613072-14651968 bp, - strand Genetic Position: Chr9, 4.25 cM
• Alliance: Piwil4^tm1.1Wyan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229360
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 9. A floxed neomycin resistance was inserted downstream of exon 12. Cre-mediated recombination removed the selection cassette and left exons 9 through 12 floxed. (J:229360)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Piwil4 Mutation: 49 strains or lines available

References

• Original: J:229360 Bao J, et al., Conditional inactivation of Miwi2 reveals that MIWI2 is only essential for prospermatogonial development in mice. Cell Death Differ. 2014 May;21(5):783-96
• All: 1 reference(s)