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Vps33btm1.1Arte
Targeted Allele Detail
Nomenclature
Symbol: Vps33btm1.1Arte
Name: vacuolar protein sorting 33B; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5770088
Synonyms: Vps33bfl
Gene: Vps33b  Location: Chr7:80269621-80291579 bp, + strand  Genetic Position: Chr7, 45.59 cM
Abnormal collagen structure in Vipas39tm1c(KOMP)Mbp/Vipas39tm1c(KOMP)Mbp Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+, and Vps33btm1.1Arte/Vps33btm1.1Arte Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ mouse tail tendon

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:222766
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 2 and 3 were floxed. The final allele lacks a selection cassette, leaving an FRT site upstream of exon 2. (J:222766)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vps33b Mutation:  18 strains or lines available
References
Original:  J:222766 Bem D, et al., VPS33B regulates protein sorting into and maturation of alpha-granule progenitor organelles in mouse megakaryocytes. Blood. 2015 Jul 9;126(2):133-43
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory