Setd2^{tm1a(NCOM)Mfgc}
Targeted Allele Detail

Summary

• Symbol: Setd2^{tm1a(NCOM)Mfgc}
• Name: SET domain containing 2; targeted mutation 1a, Mammalian Functional Genomics Centre
• MGI ID: MGI:5765972
• Gene: Setd2 Location: Chr9:110361368-110447703 bp, + strand Genetic Position: Chr9, 60.0 cM
• Alliance: Setd2^{tm1a(NCOM)Mfgc} page
• IMPC: Setd2 gene page

Mutation origin

• Mutant Cell Lines: M00019_C_361W_B08, M00019_C_361W_C09, M00019_C_361W_C11, M00019_C_361W_D11
• Germline Transmission: Earliest citation of germline transmission: J:165964
• Parent Cell Line: C2 (Tcp) (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: NorCOMM

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_MFGC3
• Mutation details: An FRT site, a LacZ reporter gene cassette, a loxP site, a neomycin resistance gene cassette, and a loxP site were inserted into intron 1. An additional loxP site was inserted into intron 2. This creates a reporter null allele. (J:165964, J:243973)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Setd2 Mutation: 102 strains or lines available

References

• Original: J:165964 Mammalian Functional Genomics Centre, Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba. MGI Direct Data Submission. 2010
• All: 2 reference(s)