Zfp521^tm1.1Qima
Targeted Allele Detail

Summary

• Symbol: Zfp521^tm1.1Qima
• Name: zinc finger protein 521; targeted mutation 1.1, Qiufu Ma
• MGI ID: MGI:5763627
• Synonyms: Zfp521^F
• Gene: Zfp521 Location: Chr18:13820070-14105812 bp, - strand Genetic Position: Chr18, 7.68 cM
• Alliance: Zfp521^tm1.1Qima page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221586
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:221586)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp521 Mutation: 51 strains or lines available

References

• Original: J:221586 Lou S, et al., Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors. J Neurosci. 2015 Apr 1;35(13):5317-29
• All: 1 reference(s)