Rasd2^tm1.1Rdl
Targeted Allele Detail

Summary

• Symbol: Rasd2^tm1.1Rdl
• Name: RASD family, member 2; targeted mutation 1.1, Roberto Di Lauro
• MGI ID: MGI:5763568
• Gene: Rasd2 Location: Chr8:75940572-75950741 bp, + strand Genetic Position: Chr8, 35.61 cM
• Alliance: Rasd2^tm1.1Rdl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223351
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: A targeting vector was used to insert a stop codon in each frame immediately downstream of the endogenous translational start codon. An IRES-EGFP was placed downstream of the endogenous regulatory sequences and a floxed PGKneo were also inserted. Cre-mediated recombination removed the neomycin resistance cassette. (J:223351)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasd2 Mutation: 18 strains or lines available

References

• Original: J:223351 Sciamanna G, et al., Rhes regulates dopamine D2 receptor transmission in striatal cholinergic interneurons. Neurobiol Dis. 2015 Jun;78:146-61
• All: 4 reference(s)