Cbx3^tm1.1Yugo
Targeted Allele Detail

Summary

• Symbol: Cbx3^tm1.1Yugo
• Name: chromobox 3; targeted mutation 1.1, Yukiko Gotoh
• MGI ID: MGI:5763388
• Synonyms: HP1gamma^fl
• Gene: Cbx3 Location: Chr6:51447596-51460684 bp, + strand Genetic Position: Chr6, 24.89 cM, cytoband B-C
• Alliance: Cbx3^tm1.1Yugo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:230288
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 (originally identified as exon 1). An FRT-flanked neomycin resistance cassette with 5' loxP site was inserted downstream of exon 3 (originally identified as exon 1). Flp-mediated recombination removed the selection cassette and left exon 3 (originally identified as exon 1) floxed. (J:230288)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbx3 Mutation: 64 strains or lines available

References

• Original: J:230288 Oshiro H, et al., Up-regulation of HP1gamma expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex. Genes Cells. 2015 Feb;20(2):108-20
• All: 1 reference(s)