Slc38a4^tm2Kel
Targeted Allele Detail

Summary

• Symbol: Slc38a4^tm2Kel
• Name: solute carrier family 38, member 4; targeted mutation 2, Gavin Derek Kelsey
• MGI ID: MGI:5763185
• Synonyms: DeltaCG1A, Slc38a4^tm2Kel
• Gene: Slc38a4 Location: Chr15:96892701-96953837 bp, - strand Genetic Position: Chr15, 52.77 cM
• Alliance: Slc38a4^tm2Kel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: The maternal germline-derived differential methylation region (DMR), which is the putative imprinting control region for this gene, was replaced by a loxP-flanked "neo:URA:tACE-Cre" cassette containing a neomycin resistance gene, a yeast orotidine-5' phosphate decarboxylase gene, and the Cre recombinase coding sequence under control of the testis-specific promoter of the angiotensin-converting enzyme gene. The cassette was excised by Cre recombinase upon passage through the male germline, leaving a single loxP site in place of the DMR. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc38a4 Mutation: 118 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)