Adipor1^tm1.1Ngb
Targeted Allele Detail

Summary

• Symbol: Adipor1^tm1.1Ngb
• Name: adiponectin receptor 1; targeted mutation 1.1, Nicolas G Bazan
• MGI ID: MGI:5762867
• Gene: Adipor1 Location: Chr1:134343116-134361089 bp, + strand Genetic Position: Chr1, 58.22 cM, cytoband E4
• Alliance: Adipor1^tm1.1Ngb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229207
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3 loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 2 through 4 and the selection cassette. (J:229207)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipor1 Mutation: 44 strains or lines available

References

• Original: J:229207 Rice DS, et al., Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival. Nat Commun. 2015;6:6228
• All: 1 reference(s)