Fzd7^tm1.1Pdcq
Targeted Allele Detail

Summary

• Symbol: Fzd7^tm1.1Pdcq
• Name: frizzled class receptor 7; targeted mutation 1.1, Pascale Dufourcq
• MGI ID: MGI:5762660
• Synonyms: fzd7^floxP, fzd7^L
• Gene: Fzd7 Location: Chr1:59521583-59526114 bp, + strand Genetic Position: Chr1, 30.08 cM
• Alliance: Fzd7^tm1.1Pdcq page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:230008
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the translation initiation site. A second loxP site was inserted donwstream of the stop site. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the stop site. (J:230008)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzd7 Mutation: 38 strains or lines available

References

• Original: J:230008 Ferreira Tojais N, et al., Frizzled7 controls vascular permeability through the Wnt-canonical pathway and cross-talk with endothelial cell junction complexes. Cardiovasc Res. 2014 Jul 15;103(2):291-303
• All: 3 reference(s)