Vgf^tm4Srjs
Targeted Allele Detail

Summary

• Symbol: Vgf^tm4Srjs
• Name: VGF nerve growth factor inducible; targeted mutation 4, Stephen R J Salton
• MGI ID: MGI:5759819
• Synonyms: Vgf^flox, Vgf^flpflox
• Gene: Vgf Location: Chr5:137055246-137062205 bp, + strand Genetic Position: Chr5, 76.13 cM
• Alliance: Vgf^tm4Srjs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222041
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into the 5'UTR. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted into the 3' UTR. (J:222041)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vgf Mutation: 26 strains or lines available

References

• Original: J:222041 Sadahiro M, et al., Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: analysis of "humanized" knockin mice expressing full-length or truncated VGF. Endocrinology. 2015 May;156(5):1724-38
• All: 5 reference(s)