Emilin2^tm1.1Jhp
Targeted Allele Detail

Summary

• Symbol: Emilin2^tm1.1Jhp
• Name: elastin microfibril interfacer 2; targeted mutation 1.1, Jane Hoover-Plow
• MGI ID: MGI:5755384
• Synonyms: E2^flox
• Gene: Emilin2 Location: Chr17:71559167-71618551 bp, - strand Genetic Position: Chr17, 41.87 cM
• Alliance: Emilin2^tm1.1Jhp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226863
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:226863)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emilin2 Mutation: 56 strains or lines available

References

• Original: J:226863 Huang M, et al., EMILIN2 regulates platelet activation, thrombus formation, and clot retraction. PLoS One. 2015;10(2):e0115284
• All: 1 reference(s)