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Klrb1btm1.1Apma
Targeted Allele Detail
Nomenclature
Symbol: Klrb1btm1.1Apma
Name: killer cell lectin-like receptor subfamily B member 1B; targeted mutation 1.1, Andrew P Makrigiannis
MGI ID: MGI:5755236
Synonyms: Nkrp1blox
Gene: Klrb1b  Location: Chr6:128813706-128826315 bp, - strand  Genetic Position: Chr6, 63.09 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:222057
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic region encompassing exons 2 - 5 was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:222057)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klrb1b Mutation:  1 strain or line available
References
Original:  J:222057 Rahim MM, et al., The mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate immune responses. Blood. 2015 Apr 2;125(14):2217-27
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory