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Atl3em1(IMPC)Tcp
Endonuclease-mediated Allele Detail
Summary
Symbol: Atl3em1(IMPC)Tcp
Name: atlastin GTPase 3; endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI ID: MGI:5754584
Gene: Atl3  Location: Chr19:7471178-7515974 bp, + strand  Genetic Position: Chr19, 5.32 cM
Alliance: Atl3em1(IMPC)Tcp page
IMPC: Atl3 gene page
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele produced from project TCPR0366 at TCP by injecting Cas9 mRNA and two guide RNAs with the spacer sequences TGGAAAACCTGGTCCAGTGC and GATCTCGGATATGGTCTTGG in ENSMUSE00000144777. This resulted in a 83-bp deletion from Chr19:7509375 to 7509457 (GRCm38). (J:165963)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Atl3 Mutation:  56 strains or lines available
References
Original:  J:165963 Centre for Modeling Human Disease, Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto. MGI Direct Data Submission. 2010;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory