Dnmt1tm9.1Jrc
Targeted Allele Detail
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Symbol: |
Dnmt1tm9.1Jrc |
Name: |
DNA methyltransferase 1; targeted mutation 9.1, Richard Chaillet |
MGI ID: |
MGI:5752890 |
Synonyms: |
Dnmt1ASA |
Gene: |
Dnmt1 Location: Chr9:20818501-20871084 bp, - strand Genetic Position: Chr9, 7.66 cM
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Alliance: |
Dnmt1tm9.1Jrc page
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Allele Type: |
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Targeted |
Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: Exon 13 was replaced with a floxed neomycin resistance cassette and a modified exon 13 in which nucleotide substitutions replaced the amino acids ESH with ASA within the mouse-rat differential region of the intrisically disordered domain (IDD). Cre-mediated recombination removed the selection cassette.
(J:223970)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dnmt1 Mutation: |
108 strains or lines available
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Original: |
J:223970 Shaffer B, et al., The DNMT1 intrinsically disordered domain regulates genomic methylation during development. Genetics. 2015 Feb;199(2):533-41 |
All: |
1 reference(s) |
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