Prkd1^tm1.2Aha
Targeted Allele Detail

Summary

• Symbol: Prkd1^tm1.2Aha
• Name: protein kinase D1; targeted mutation 1.2, Akihiro Harada
• MGI ID: MGI:5752361
• Synonyms: PKD1^-
• Gene: Prkd1 Location: Chr12:50388014-50695881 bp, - strand Genetic Position: Chr12, 21.78 cM, cytoband C1
• Alliance: Prkd1^tm1.2Aha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229519
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked splice acceptor-pgk-beta-geo-polyA cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed the FRT flanked cassette and exon 2. (J:229519)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkd1 Mutation: 58 strains or lines available

References

• Original: J:229519 Atik N, et al., The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution. Cell Struct Funct. 2014;39(1):61-77
• All: 1 reference(s)