Ildr1^tm1Lwa
Targeted Allele Detail

Summary

• Symbol: Ildr1^tm1Lwa
• Name: immunoglobulin-like domain containing receptor 1; targeted mutation 1, Lei Wang
• MGI ID: MGI:5752278
• Gene: Ildr1 Location: Chr16:36514340-36547166 bp, + strand Genetic Position: Chr16, 25.88 cM
• Alliance: Ildr1^tm1Lwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221594
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A construct consisting of an FRT site, splice acceptor site, IRES, LacZ gene, loxP site neo cassette, FRT site and loxP site was inserted upstream of exon 2 and a loxP site was inserted downstream of exon 3 via homologous recombination. (J:221594)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ildr1 Mutation: 37 strains or lines available

References

• Original: J:221594 Sang Q, et al., ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42. Biol Open. 2015 Mar 27;4(4):411-8
• All: 1 reference(s)