Schip1tm1.1Lgo
Targeted Allele Detail
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Symbol: |
Schip1tm1.1Lgo |
Name: |
schwannomin interacting protein 1; targeted mutation 1.1, Laurence Goutebroze |
MGI ID: |
MGI:5751809 |
Synonyms: |
Schip1delta10 |
Gene: |
Schip1 Location: Chr3:67972135-68533814 bp, + strand Genetic Position: Chr3, 31.44 cM, cytoband E2
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Alliance: |
Schip1tm1.1Lgo page
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Germline Transmission: |
Earliest citation of germline transmission:
J:221642
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 10 and a floxed EGFP/hygro cassette was inserted downstream of exon 11 via homologous recombination. Cre mediated recombination removed exon 10 and the EGFP/hygro cassette. Immunoblot analysis revealed the absence of both all wild-type isoforms and any truncated proteins in homozygous mutant mice.
(J:221642)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Schip1 Mutation: |
36 strains or lines available
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Original: |
J:221642 Klingler E, et al., The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36 |
All: |
2 reference(s) |
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