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Targeted Allele Detail
Symbol: Pld1tm1.2Gdp
Name: phospholipase D1; targeted mutation 1.2, Gilbert Di Paolo
MGI ID: MGI:5751724
Synonyms: Pld1Flox
Gene: Pld1  Location: Chr3:27992844-28187511 bp, + strand  Genetic Position: Chr3, 11.15 cM
Germline Transmission:  Earliest citation of germline transmission: J:207283
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129/SvJ
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 13. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 14. FLP-mediated recombination removed the neo cassette. (J:207283)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pld1 Mutation:  42 strains or lines available
Original:  J:207283 Dall'Armi C, et al., The phospholipase D1 pathway modulates macroautophagy. Nat Commun. 2010;1:142
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory