Insm1^tm3.1Cbm
Targeted Allele Detail

Summary

• Symbol: Insm1^tm3.1Cbm
• Name: insulinoma-associated 1; targeted mutation 3.1, Carmen Birchmeier
• MGI ID: MGI:5751685
• Synonyms: Insm1^flox
• Gene: Insm1 Location: Chr2:146064021-146066940 bp, + strand Genetic Position: Chr2, 71.33 cM
• Alliance: Insm1^tm3.1Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221186
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted 5' of the coding region and a loxP site was inserted 3' of the coding region. Flp mediated recombination removed the neo cassette. (J:221186)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Insm1 Mutation: 13 strains or lines available

References

• Original: J:221186 Jia S, et al., Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic beta-cell function. EMBO J. 2015 May 12;34(10):1417-33
• All: 4 reference(s)