Sat1^tm1.1Kzah
Targeted Allele Detail

Summary

• Symbol: Sat1^tm1.1Kzah
• Name: spermidine/spermine N1-acetyl transferase 1; targeted mutation 1.1, Kamyar Zahedi
• MGI ID: MGI:5751527
• Synonyms: SSAT-Cko^Neo-/FLP-
• Gene: Sat1 Location: ChrX:153996128-153999345 bp, - strand Genetic Position: ChrX, 72.38 cM, cytoband F3-F4
• Alliance: Sat1^tm1.1Kzah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229304
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT- and loxP-site flanked neomycin resistance cassette was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 1 through 3 floxed. (J:229304)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sat1 Mutation: 9 strains or lines available

References

• Original: J:229304 Zahedi K, et al., Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G546-60
• All: 4 reference(s)