Myb^tm1Hska
Targeted Allele Detail

Summary

• Symbol: Myb^tm1Hska
• Name: Myb proto-oncogene, transcription factor; targeted mutation 1, Hiroshi Sakamoto
• MGI ID: MGI:5751426
• Synonyms: Myb^egfp
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^tm1Hska page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223579
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted into exon 16 at the STOP codon (replacing it) a 30 amino acid linker and EGFP to create an in-frame reporter fusion. A neomycin resistance cassette was inserted upstream of the modified exon 16. (J:223579)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 56 strains or lines available

References

• Original: J:223579 Sakamoto H, et al., Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Stem Cells. 2015 Feb;33(2):479-90
• All: 2 reference(s)