Cers4^tm1.2Arte
Targeted Allele Detail

Summary

• Symbol: Cers4^tm1.2Arte
• Name: ceramide synthase 4; targeted mutation 1.2, TaconicArtemis
• MGI ID: MGI:5751278
• Synonyms: CerS4^-
• Gene: Cers4 Location: Chr8:4542863-4579603 bp, + strand Genetic Position: Chr8, 2.04 cM, cytoband A1.2
• Alliance: Cers4^tm1.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221051
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and FRT flanked puro cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the puro cassette and exon 3. (J:221051)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cers4 Mutation: 44 strains or lines available

References

• Original: J:221051 Peters F, et al., Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling. J Invest Dermatol. 2015 Jun;135(6):1501-9
• All: 4 reference(s)