Atoh7^{tm3(Atoh7/tTA)Whk}
Targeted Allele Detail

Summary

• Symbol: Atoh7^{tm3(Atoh7/tTA)Whk}
• Name: atonal bHLH transcription factor 7; targeted mutation 3, William H Klein
• MGI ID: MGI:5750904
• Synonyms: Atoh7-tTA
• Gene: Atoh7 Location: Chr10:62935564-62937059 bp, + strand Genetic Position: Chr10, 32.54 cM
• Alliance: Atoh7^{tm3(Atoh7/tTA)Whk} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228990
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Transactivator)
• Mutation: Insertion
• Mutation details: The targeting construct introduced an Atoh7 and tetracycline-controlled transactivator (tTA) fusion gene into the locus. (J:228990)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh7 Mutation: 9 strains or lines available

References

• Original: J:228990 Gao Z, et al., Transcriptome of Atoh7 retinal progenitor cells identifies new Atoh7-dependent regulatory genes for retinal ganglion cell formation. Dev Neurobiol. 2014 Nov;74(11):1123-40
• All: 1 reference(s)