Klf2tm1.1Hhn
Targeted Allele Detail
|
Symbol: |
Klf2tm1.1Hhn |
Name: |
Kruppel-like transcription factor 2 (lung); targeted mutation 1.1, Huck Hui Ng |
MGI ID: |
MGI:5750068 |
Gene: |
Klf2 Location: Chr8:73072906-73075498 bp, + strand Genetic Position: Chr8, 34.99 cM, cytoband C1
|
Alliance: |
Klf2tm1.1Hhn page
|
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: The L1L2_Bact_P cassette was inserted at a position on Chromosome 8, resulting in a 1594bp deletion starting at position 72319391 and ending at position 72320985, including exons 2 and 3 of the Klf2 gene. The targeting vector is composed of an FRT site followed by En2SA (mouse engrailed 2 gene splice acceptor), IRES-lacZ sequence, a loxP site, a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Cre-mediated recombination removed the floxed neomycin cassette.
(J:228270)
|
|
|
|
Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
All: |
4 reference(s) |
|