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Angpt1tm2.1Sjm
Targeted Allele Detail
Nomenclature
Symbol: Angpt1tm2.1Sjm
Name: angiopoietin 1; targeted mutation 2.1, Sean J Morrison
MGI ID: MGI:5749674
Synonyms: Angpt1fl
Gene: Angpt1  Location: Chr15:42288119-42540373 bp, - strand  Genetic Position: Chr15, 16.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:220459
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsAn FRT flanked neo cassette and loxP site were inserted upstream of exon 1 and a loxP site was inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:220459)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Angpt1 Mutation:  21 strains or lines available
References
Original:  J:220459 Zhou BO, et al., Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1. Elife. 2015;4
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory