Crlf2^tm1.1Sfz
Targeted Allele Detail

Summary

• Symbol: Crlf2^tm1.1Sfz
• Name: cytokine receptor-like factor 2; targeted mutation 1.1, Steven F Ziegler
• MGI ID: MGI:5708846
• Synonyms: Tslpr^fl
• Gene: Crlf2 Location: Chr5:109702575-109706859 bp, - strand Genetic Position: Chr5, 53.24 cM
• Alliance: Crlf2^tm1.1Sfz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219531
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:219531)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crlf2 Mutation: 21 strains or lines available

References

• Original: J:219531 Han H, et al., Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis. J Clin Invest. 2014 Dec;124(12):5442-52
• All: 8 reference(s)