Tmem100^tm2.1Xzd
Targeted Allele Detail

Summary

• Symbol: Tmem100^tm2.1Xzd
• Name: transmembrane protein 100; targeted mutation 2.1, Xinzhong Dong
• MGI ID: MGI:5708590
• Synonyms: Tmem100^fl
• Gene: Tmem100 Location: Chr11:89921174-89927334 bp, + strand Genetic Position: Chr11, 54.75 cM
• Alliance: Tmem100^tm2.1Xzd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219559
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3, which contains the entire coding region, and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:219559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem100 Mutation: 16 strains or lines available

References

• Original: J:219559 Weng HJ, et al., Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46
• All: 2 reference(s)