Gps2^tm1Jsz
Targeted Allele Detail

Summary

• Symbol: Gps2^tm1Jsz
• Name: G protein pathway suppressor 2; targeted mutation 1, Jinsong Zhang
• MGI ID: MGI:5708370
• Gene: Gps2 Location: Chr11:69804714-69807417 bp, + strand Genetic Position: Chr11, 42.92 cM
• Alliance: Gps2^tm1Jsz page

Gps2^tm1Jsz/Gps2^tm1Jsz mice die prenatally around embryonic day 10

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219351
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A region including the coding portion of exon 1 and all of exon 2 was replaced with a neo cassette via homologous recombination. (J:219351)

Generation of the Gps2^tm1Jsz allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gps2 Mutation: 21 strains or lines available

References

• Original: J:219351 Guo C, et al., The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor gamma requires G protein pathway suppressor 2. J Biol Chem. 2015 Feb 6;290(6):3666-79
• All: 1 reference(s)