About   Help   FAQ
Hdac11tm1.2Mrl
Targeted Allele Detail
Nomenclature
Symbol: Hdac11tm1.2Mrl
Name: histone deacetylase 11; targeted mutation 1.2, Merck Research Laboratory
MGI ID: MGI:5707970
Synonyms: Hdac11tm1Mrl
Gene: Hdac11  Location: Chr6:91156670-91174692 bp, + strand  Genetic Position: Chr6, 40.38 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:228570
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
    The loxP flanked exon 3 was removed via Cre-mediated recombination generating a frame shift. (J:245003)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hdac11 Mutation:  10 strains or lines available
References
Original:  J:228570 Cheng F, et al., Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells. Mol Immunol. 2014 Jul;60(1):44-53
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory