Mirc19^tm1.2Tfko
Targeted Allele Detail

Summary

• Symbol: Mirc19^tm1.2Tfko
• Name: microRNA cluster 19, including Mir212 through Mir132; targeted mutation 1.2, Taro Fukao
• MGI ID: MGI:5707393
• Synonyms: Mir212-Mir132^-
• Gene: Mirc19 Location: Chr11:75064214-75064573 bp Genetic Position: Chr11, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220127
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mirc19^tm1.2Tfko involves 2 genes/genome features (Mir212, Mir132) View all
• Mutation details: An FRT-flanked neomycin selection cassette with a 3' loxP site was inserted upstream of Mir212 and an additional loxP site was inserted downstream of Mir132. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the microRNAs. (J:220127)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc19 Mutation: 0 strains or lines available

References

• Original: J:220127 Kayo H, et al., miR-212 and miR-132 are dispensable for mouse mammary gland development. Nat Genet. 2014 Aug;46(8):802-4
• All: 1 reference(s)