Elp1^tm1.1Wgt
Targeted Allele Detail

Summary

• Symbol: Elp1^tm1.1Wgt
• Name: elongator complex protein 1; targeted mutation 1.1, Warren Tourtellotte
• MGI ID: MGI:5705644
• Synonyms: elp1^f
• Gene: Elp1 Location: Chr4:56749680-56802331 bp, - strand Genetic Position: Chr4, 31.66 cM
• Alliance: Elp1^tm1.1Wgt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221263
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 20. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 20. Flp-mediated recombination removed the selection cassette and left exon 20 floxed. (J:221263)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elp1 Mutation: 72 strains or lines available

References

• Original: J:221263 Jackson MZ, et al., A neuron autonomous role for the familial dysautonomia gene ELP1 in sympathetic and sensory target tissue innervation. Development. 2014 Jun;141(12):2452-61
• All: 1 reference(s)