Clec1b^tm1.1Crs
Targeted Allele Detail

Summary

• Symbol: Clec1b^tm1.1Crs
• Name: C-type lectin domain family 1, member b; targeted mutation 1.1, Caetano Reis e Sousa
• MGI ID: MGI:5705315
• Synonyms: Clec1b^fl
• Gene: Clec1b Location: Chr6:129374260-129382376 bp, + strand Genetic Position: Chr6, 63.3 cM, cytoband F3
• Alliance: Clec1b^tm1.1Crs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217480
• Parent Cell Line: PRX-B6N (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:217480)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec1b Mutation: 17 strains or lines available

References

• Original: J:217480 Acton SE, et al., Dendritic cells control fibroblastic reticular network tension and lymph node expansion. Nature. 2014 Oct 23;514(7523):498-502
• All: 3 reference(s)