Avpr1a^tm2.1Zrd
Targeted Allele Detail

Summary

• Symbol: Avpr1a^tm2.1Zrd
• Name: arginine vasopressin receptor 1A; targeted mutation 2.1, Zoe R Donaldson
• MGI ID: MGI:5704071
• Synonyms: pvKI-short
• Gene: Avpr1a Location: Chr10:122284404-122289357 bp, + strand Genetic Position: Chr10, 70.36 cM, cytoband D3
• Alliance: Avpr1a^tm2.1Zrd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223196
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: 3.4 kb of the 5' flanking region was replaced with the corresponding sequence from prairie vole with the short variant of the microsatellite element. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted upstream of the replaced sequence. (J:223196)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Avpr1a Mutation: 40 strains or lines available

References

• Original: J:223196 Donaldson ZR, et al., The relative contribution of proximal 5' flanking sequence and microsatellite variation on brain vasopressin 1a receptor (Avpr1a) gene expression and behavior. PLoS Genet. 2013 Aug;9(8):e1003729
• All: 1 reference(s)