Tg(ABCB1-luc)1Egsch
Transgene Detail

Summary

• Symbol: Tg(ABCB1-luc)1Egsch
• Name: transgene insertion 1, Erin Schuetz
• MGI ID: MGI:5704068
• Synonyms: MDR1-Luc
• Transgene: Tg(ABCB1-luc)1Egsch Location: unknown Genetic Position: Chr3, Syntenic
• Alliance: Tg(ABCB1-luc)1Egsch page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The MDR1-luc transgene was designed to contain approximately 10 kb of 5'-flanking sequences from the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 locus (ABCB1; including the promoter and regulatory nuclear response elements) upstream of a firefly luciferase sequence (luc). (J:227043)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:227043 Yasuda K, et al., In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice. Drug Metab Dispos. 2015 Nov;43(11):1646-54
• All: 1 reference(s)