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Tg(ABCB1-luc)1Egsch
Transgene Detail
Nomenclature
Symbol: Tg(ABCB1-luc)1Egsch
Name: transgene insertion 1, Erin Schuetz
MGI ID: MGI:5704068
Synonyms: MDR1-Luc
Transgene: Tg(ABCB1-luc)1Egsch  Location: unknown  Genetic Position: Chr3, Syntenic
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe MDR1-luc transgene was designed to contain approximately 10 kb of 5'-flanking sequences from the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 locus (ABCB1; including the promoter and regulatory nuclear response elements) upstream of a firefly luciferase sequence (luc). (J:227043)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:227043 Yasuda K, et al., In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice. Drug Metab Dispos. 2015 Nov;43(11):1646-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory