About   Help   FAQ
Transgene Detail
Symbol: Tg(ABCB1-luc)1Egsch
Name: transgene insertion 1, Erin Schuetz
MGI ID: MGI:5704068
Synonyms: MDR1-Luc
Transgene: Tg(ABCB1-luc)1Egsch  Location: unknown  Genetic Position: Chr3, Syntenic
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe MDR1-luc transgene was designed to contain approximately 10 kb of 5'-flanking sequences from the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 locus (ABCB1; including the promoter and regulatory nuclear response elements) upstream of a firefly luciferase sequence (luc). (J:227043)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:227043 Yasuda K, et al., In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice. Drug Metab Dispos. 2015 Nov;43(11):1646-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.16
The Jackson Laboratory