Hira^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Hira^tm1.1Arte
• Name: histone cell cycle regulator; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5702965
• Synonyms: Hirafl
• Gene: Hira Location: Chr16:18695787-18789059 bp, + strand Genetic Position: Chr16, 11.69 cM, cytoband A-B1
• Alliance: Hira^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217374
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 6 and 7 are floxed. There is also a single FRT site upstream of exon 6 and an F3 site downstream of exon 7. (J:217374)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hira Mutation: 74 strains or lines available

References

• Original: J:217374 Rai TS, et al., HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia. Genes Dev. 2014 Dec 15;28(24):2712-25
• All: 3 reference(s)