Marco^{tm2b(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Marco^{tm2b(EUCOMM)Hmgu}
• Name: macrophage receptor with collagenous structure; targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5701720
• Gene: Marco Location: Chr1:120402267-120432753 bp, - strand Genetic Position: Chr1, 52.71 cM, cytoband E4-F
• Alliance: Marco^{tm2b(EUCOMM)Hmgu} page
• IMPC: Marco gene page

Mutation origin

• Mutant Cell Line: HEPD0664_5_D06
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Marco^{tm2e(EUCOMM)Hmgu} allele resulted in the removal of the promoter-driven neomycin selection cassette leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Marco Mutation: 34 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 2 reference(s)