Tg(MMTV-Fgfr1)4775Jmr
Transgene Detail

Summary

• Symbol: Tg(MMTV-Fgfr1)4775Jmr
• Name: transgene insertion 4775, Jeffrey Rosen
• MGI ID: MGI:5701640
• Synonyms: iFGFR1, iR1, line 4775, MMTV-iFGFR1
• Transgene: Tg(MMTV-Fgfr1)4775Jmr Location: unknown
• Alliance: Tg(MMTV-Fgfr1)4775Jmr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Fgfr1)4775Jmr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgfr1 (MGI:95522)

• Mutation details: The transgene expresses mouse Fgfr1 under the control of MMTV. Three founder lines transmitted the transgene to the germline and one was found to be expressed in the mammary gland at low levels (line 4775). (J:76468)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-Fgfr1)4775Jmr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:76468 Welm BE, et al., Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol. 2002 May 13;157(4):703-14
• All: 7 reference(s)