Tg(Actl6b-cre)4092Jiwu
Transgene Detail

Summary

• Symbol: Tg(Actl6b-cre)4092Jiwu
• Name: transgene insertion 4092, Jie Wu
• MGI ID: MGI:5699179
• Synonyms: BAF53b-Cre
• Transgene: Tg(Actl6b-cre)4092Jiwu Location: unknown
• Alliance: Tg(Actl6b-cre)4092Jiwu page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Actl6b-cre)4092Jiwu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Actl6b (MGI:1933548)

• Mutation details: The mouse bacterial artificial chromosome (BAC) RP23-127E17 containing the entire Actl6b gene and approximately 100 kb flanking sequence, was modified by replacing the first 2 exons of the Actl6b gene with the PCR product of the cre recombinase gene and Actl6b 3' UTR, which situates the cre gene just downstream of the start codon. Founder line 4092 was subsequently established. (J:224076)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Actl6b (mouse) Summary of all recombinase alleles driven by Actl6b. Comparative matrix view of recombinase activities Alliance mouse Actl6b gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:224076 Zhan X, et al., Generation of BAF53b-Cre transgenic mice with pan-neuronal Cre activities. Genesis. 2015 Jul;53(7):440-8
• All: 14 reference(s)