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Auts2tm1.1Dare
Targeted Allele Detail
Nomenclature
Symbol: Auts2tm1.1Dare
Name: autism susceptibility candidate 2; targeted mutation 1.1, Danny Reinberg
MGI ID: MGI:5697527
Gene: Auts2  Location: Chr5:131437682-132542343 bp, - strand  Genetic Position: Chr5, 70.66 cM, cytoband G1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217675
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsMice carrying Auts1 were crossed with FLP mice to excise the FRT flanking sequence, resulting in loxP sites flanking exon 7 of the gene. (J:217675)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Auts2 Mutation:  9 strains or lines available
References
Original:  J:217675 Gao Z, et al., An AUTS2-Polycomb complex activates gene expression in the CNS. Nature. 2014 Dec 18;516(7531):349-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory