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Kcnc2tm1.1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Kcnc2tm1.1(KOMP)Vlcg
Name: potassium voltage gated channel, Shaw-related subfamily, member 2; targeted mutation 1.1, Velocigene
MGI ID: MGI:5695975
Gene: Kcnc2  Location: Chr10:112271121-112467024 bp, + strand  Genetic Position: Chr10, 60.3 cM
Mutation
origin
Mutant Cell Line:  15577A-F7
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsCre-mediated excision of the parental Kcnc2tm1(KOMP)Vlcg allele resulted in the removal of the neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Expression
In Mice Carrying this Mutation: 48 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnc2 Mutation:  3 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory