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Kcnt2tm1.1Clin
Targeted Allele Detail
Nomenclature
Symbol: Kcnt2tm1.1Clin
Name: potassium channel, subfamily T, member 2; targeted mutation 1.1, Christopher J Lingle
MGI ID: MGI:5694651
Synonyms: Slick floxed
Gene: Kcnt2  Location: Chr1:140173896-140539805 bp, + strand  Genetic Position: Chr1, 61.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  B6/BLU (ES Cell)
Strain of Origin:  C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 22 and a second loxP site downstream of exon22, followed by an FRT-flanked neomycin resistance (neo) cassette which includes a third loxP site. FLP-mediated recombination removed the FRT-flanked neo cassette leaving exon 22 floxed. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnt2 Mutation:  76 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory