Afap1l2^tm1Mliu
Targeted Allele Detail

Summary

• Symbol: Afap1l2^tm1Mliu
• Name: actin filament associated protein 1-like 2; targeted mutation 1, Mingyao Liu
• MGI ID: MGI:5694601
• Synonyms: Xb130^flox
• Gene: Afap1l2 Location: Chr19:56900793-56996660 bp, - strand Genetic Position: Chr19, 52.04 cM
• Alliance: Afap1l2^tm1Mliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223478
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 7 and a Frt-flanked neo cassette with 3' loxP sequence were inserted downstream of exon 7. Flp mediated recombination removed the neo cassette leaving loxP-flanked exon 7. (J:223478)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Afap1l2 Mutation: 44 strains or lines available

References

• Original: J:223478 Zhao J, et al., XB130 deficiency affects tracheal epithelial differentiation during airway repair. PLoS One. 2014;9(10):e108952
• All: 1 reference(s)