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Tg(tetO-DRD3)3-10Kndl
Transgene Detail
Nomenclature
Symbol: Tg(tetO-DRD3)3-10Kndl
Name: transgene insertion 3-10, Eric R Kandel
MGI ID: MGI:5693547
Synonyms: tetO-D3R
Transgene: Tg(tetO-DRD3)3-10Kndl  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-DRD3)3-10Kndl expresses 1 gene
 
Mutation detailsThe tetO promoter consisting of seven operator sequences of the E. coli Tn10 tetracycline resistance operon and a Cytomegalovirus (CMV) minimal promoter, drives expression of the human DRD3 (D3R) gene and hGHpA (2.1 kb of the human growth hormone gene harboring the hGH polyadenylation signal). (J:225565)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:225565 Simpson EH, et al., Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition. Biol Psychiatry. 2014 Nov 15;76(10):823-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory