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Gfpt1tm1c(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Gfpt1tm1c(EUCOMM)Wtsi
Name: glutamine fructose-6-phosphate transaminase 1; targeted mutation 1c, Wellcome Trust Sanger Institute
MGI ID: MGI:5692888
Gene: Gfpt1  Location: Chr6:87042846-87092197 bp, + strand  Genetic Position: Chr6, 37.81 cM
Mutation
origin
Mutant Cell Line:  EPD0069_2_H11
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation detailsFlp-mediated excision of the parental Gfpt1tm1a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and the inserted lacZ reporter sequence, leaving behind critical exon 7 flanked by loxP sites. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gfpt1 Mutation:  9 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory