Pkd2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pkd2^m1Btlr
• Name: polycystin 2, transient receptor potential cation channel; mutation 1, Bruce Beutler
• MGI ID: MGI:5690203
• Synonyms: nephro
• Gene: Pkd2 Location: Chr5:104607316-104653685 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Pkd2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 56,423,352 (v38) on chromosome 5, or base pair 29,583 in the GenBank genomic region NC_000071. The mutation corresponds to residue 1,882 in the NM_008861 mRNA sequence in exon 7 of 15 total exons. The mutation results in a tryptophan (W) to arginine (G) substitution at position 568 (W568R). (J:225044)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd2 Mutation: 84 strains or lines available

References

• Original: J:225044 Prince L, et al., Mutagenetix entry for nephro. MGI Direct Data Submission. 2015
• All: 1 reference(s)